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; . Houston TranStar Center 6.2 Agriculture and mining 2.4 Architecture See also: List of hospitals in Texas Main article: Transportation in Texas Further information: climate of Houston. . . Hilshire Village In the 16th century perhaps 240,000 Europeans entered American ports. By the late 16th century gold and silver imports from America provided one-fifth of Spain's total budget, Features Kohrville Houston is a significant hub for trafficking of cocaine cannabis heroin MDMA and methamphetamine due to its size and proximity to major illegal drug exporting nations. Houston is one of the country's largest hubs for human trafficking, Main article: Spanish Civil War.

While technological superiority and cultural factors played an important role in the victories of the conquistadors in the Americas their conquest was greatly facilitated by old world diseases: smallpox chicken pox diphtheria typhus influenza measles malaria and yellow fever the diseases were carried to distant tribes and villages This typical path of disease transmission moved much faster than the conquistadors so that as they advanced resistance weakened.[citation needed] Epidemic disease is commonly cited as the primary reason for the population collapse the American natives lacked immunity to these infections. Houston has a franchise in nearly every major professional sports league including: Houston Dynamo (MLS) Houston Astros (MLB) Houston Rockets (NBA) Houston Comets (Now Defunct)(WNBA) Houston Aeros (Now Defunct) (AHL) Houston Texans (NFL) and Houston Dash (National Women's Soccer League). The Portuguese assimilated some of the native tribes while others were enslaved or exterminated in long wars or by European diseases to which they had no immunity. By the mid-16th century sugar had become Brazil's most important export and the Portuguese imported African slaves to produce it, Publicly owned, The 1492 discovery of the New World by Spain rendered desirable a delimitation of the Spanish and Portuguese spheres of exploration Thus dividing the world into two exploration and colonizing areas seemed appropriate This was accomplished by the Treaty of Tordesillas (7 June 1494) which modified the delimitation authorized by Pope Alexander VI in two bulls issued on 4 May 1493 the treaty gave to Portugal all lands which might be discovered east of a meridian drawn from the Arctic Pole to the Antarctic at a distance of 370 leagues (1,800 km) west of Cape Verde Spain received the lands west of this line.